Probiotics + enzymes, together because good health begins in the gut.
Most gut supplements pick a side: probiotics or enzymes. Pro-B is both. Live probiotics re-seed the good bacteria that keep the gut in balance, and digestive enzymes help every meal actually land instead of passing through half-used. One capsule a day does both jobs.
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120 Day Worry-Free Guarantee
Most people notice a difference within the first weeks.
Micro-encapsulated
More survives to the gut
Made in U.S.A.
Family-owned since 1999
People of all ages
Gentle enough for the whole family
120 Day
Worry-Free Guarantee
Free shipping
On orders $65+
Balance the gut. The rest follows.
Bloating, irregularity, low energy, meals that sit heavy: more of it traces back to the gut than you would think. Because good health always begins in the gut, and modern life is hard on it. Here is the pattern.
Processed meals, stress, and every course of antibiotics thin out the good bacteria the gut depends on.
2
Digestion falters
With fewer good bacteria and too few enzymes, food moves through only half-used.
3
You feel it everywhere
Bloating, irregularity, low energy: a gut out of balance never keeps it to itself.
4
Re-seed, then re-supply
Probiotics re-seed the good bacteria; digestive enzymes help every meal actually land. Pro-B does both, in one capsule.
In their own words
What people notice most.
We let the reviews speak for themselves. These are the changes that come up again and again across verified Pro-B reviews, starting with the ones we hear about most.
4.5★
Average rating
87%
Rated 4 or 5 stars
What people mention most
Steadier, more regular digestion is the change people write about most, often after years of trying other probiotics.
“I have never had consistent bowel movements before I started using this product. Now it's a daily occurrence and not difficult.” — Cheryl J., verified review
Steadier, more efficient digestion
"I have tried several probiotics and enzyme products. This one is a nice package and keeps me healthy with a better, more efficient digestive system."Robin M. · Verified review
Gut back on track after antibiotics
"Had to be on many antibiotics. These helped get me regular again and kept my stomach from getting nauseous. Still take them now, and my children too."Regan K. · Verified review
Tried other probiotics, this is the one
"Works better than any probiotic I have tried!"Becky C. · Verified review
Everyday comfort, less upset
"I changed my diet and there was some improvement, but when I started the Pro-B it has been just short of amazing for me. Will stay on."Amey B. · Verified review
An easy daily habit for the whole family
"I bought this for my parents, both over 85. After three weeks my mother said they're working, more energy, and their appetite is up too."Kenneth P. · Verified review
Trusted since 1999For people of all agesProbiotics + digestive enzymes
"I have used this product for years and it works great for me. I've tried more expensive probiotics that were supposed to be good but actually created some serious problems. Thank you for this wonderful product."Carrie O. · Verified review
Based on verified reviews for Pro-B. Bar lengths reflect how often each theme comes up, not a guaranteed result. Pro-B is a dietary supplement, not a treatment for any condition, and individual results vary.
Inside the capsule
Three strains, one balanced gut.
Most gut supplements pick a side: probiotics or enzymes. Pro-B carries both, the same blend we make as Bac-Pak Plus for pets, formulated for people. First, the probiotics. Each strain settles into a different stretch of the GI tract and does a different job: three are lactic-acid producers, together delivering 2.1 billion CFU per gram, and the fourth, Bacillus subtilis, is a hardy spore-former that survives the trip on its own.
2.1 billionCFU/g · three lactic-acid strains
Lactic-acid CFU/g
2.1billion
All strains are micro-encapsulated, protected from heat, moisture, and stomach acid so more arrives alive at the gut, where they do their work. Individual strain ratios approximate. Every batch is made to deliver 2.1 billion CFU per gram.
The other half · eight digestive enzymes
Every meal, actually landed.
Probiotics rebalance the gut. Enzymes do the work of breaking food down, so what you eat becomes what your body absorbs, instead of passing through half-used. Pro-B carries eight, each targeting a different part of the meal.
Total enzymes
8working
Full activity breakdown
Enzyme
Activity per gram
What it does
alpha-Amylase Aspergillus oryzae
18,750 µgstarch hydrolyzed/min
Breaks down starches and complex carbohydrates so they release usable energy.
Protease Aspergillus oryzae
2,500 µgamino acids hydrolyzed/min
Breaks proteins down to amino acids, the raw materials for muscle, skin, and immune cells.
Hemi-Cellulase Aspergillus niger
2,200 µghemicellulose broken-down/min
Releases trapped nutrients from plant cell walls, improving fiber digestion.
Phytase Aspergillus niger
1,200 µgphytate hydrolyzed/min
Unlocks bound minerals, phosphorus, iron, zinc, that would otherwise pass through unused.
Cellulase Aspergillus niger
1,000 µgcellulose broken-down/min
Breaks down cellulose, the structural fiber in plant matter, for better regularity.
Lipase Aspergillus oryzae
750 µgfatty acids hydrolyzed/min
Breaks fats into fatty acids, the building blocks for healthy skin, hair, and brain.
Pectinase Aspergillus oryzae
500 µgpectin broken-down/min
Breaks pectin in fruits and vegetables, easing digestion and reducing gas.
beta-Glucanase Aspergillus niger
375 µgbeta glucans hydrolyzed/min
Breaks down beta-glucans in grains for gentler, more efficient digestion.
Activity values are guaranteed minimums, made to label. µg = micrograms.
A clean carrier. The blend arrives as a pure powder in dissolvable vegetable capsules: hypoallergenic and Non-GMO, with no artificial colors, flavors, or preservatives. No refrigeration required. Made in the USA, the same way since 1999.
Trustpilot product reviews
★Trustpilot
4.3★★★★★Based on 33 verified product reviews
★★★★★
Years of use, no surprises
I have used this product for years and it works great for me. I have tried more expensive probiotics in the past that were supposed to be good but actually created some serious problems. Thank you for this wonderful product.
Carrie O. · Verified · Pro-B
★★★★★
Steady through a course of antibiotics
Had to be on many antibiotic while&after having a pregnancy issue. These helped get me regular again and kept my stomach from getting nauseous while taking the antibiotics. Still take them now and my children to keep everything going right in the gut!
Regan K. · Verified · Pro-B
★★★★★
A tidy package of probiotics and enzymes
I have tried several Probiotics and enzymes products, this one is a nice package and keeps me healthy with a better more efficient digestive system.
Robin M. · Verified · Pro-B
★★★★★
Better than the last one
I like this better than the previous probiotic I was using. Highly recommend!
Product reviews collected by Trustpilot after purchase, shown as written, longer ones excerpted. Newer reviews live in the verified reviews section below.
Probiotics for the microbiome. Enzymes for digestion. Yucca to round out the blend. No fillers, no shortcuts, nothing you can't pronounce the reason for.
Live probiotics
Four strains, 2.1 billion CFUs per gram, micro-encapsulated so more reaches the gut alive: three lactic-acid producers plus the spore-forming Bacillus subtilis.
Digestive enzymes
Eight enzymes from natural fermentation, covering starches, proteins, fats, and plant fibers, so every meal releases what's in it.
Yucca schidigera
A desert plant used for generations, included as the blend's natural botanical base that helps keep digestion comfortable.
Daily ritual
One capsule, on an empty stomach.
No weighing, no math. One capsule a day, on an empty stomach, with a glass of water, so the blend gets a clear run to the gut and is already in place when your next meal arrives.
01
Empty stomach, 8 oz of water
Take your capsule before you eat, first thing in the morning is easiest, with a full glass of water. No food in the way means more of the blend arrives where it works.
02
One per person
No dose tiers to look up. One a day for everyone — double it for the first two weeks to give the gut a running start, then settle into the daily one.
03
Make it automatic
Keep the bottle by the coffee maker or the bathroom sink, wherever your morning starts, and it becomes a habit instead of one more thing to remember.
The whole house, covered
How long does a bottle last in your house?
Everyone takes one capsule a day, so the only math is how many of you there are. Set your household and we'll size the order.
People taking Pro-B
1
Sized at the standard one-a-day amount. Doubling for the first two weeks? Your first bottle just runs a little shorter — the schedule catches up on its own.
Capsules per day1
One bottle lastsabout 3 months
Your Auto-Ship fit
1 bottle every 3 months
The comeback rhythm
What changes, and when.
A gut rebalances on its own schedule; live nutrition builds, it doesn't jolt. Here's the rhythm most people report.
Week 1
Meals start sitting easier
Less heaviness after meals, usually the first thing people notice
The enzymes go to work on day one; food starts releasing what's in it
Digestion begins finding a steadier rhythm
Weeks 2 – 4
The gut finds its balance
Regularity settles in as the good bacteria re-establish
Less bloating and gurgle between meals
Energy lifts as more of every meal gets absorbed
Month 2 onward
A steadier baseline
The balanced gut holds through travel, diet changes, and stressful weeks
Comfort after meals becomes the norm, not the exception
One bottle carries a single adult all the way here and beyond
The same idea we've trusted for pets since 1999, made for the people who love them.
Made for your dog, too
Same blend, built for the bowl.
Bac-Pak Plus is the pet version of Pro-B: the same probiotics-plus-enzymes blend, as a powder you scoop over the bowl. Good health begins in the gut, for every one of you.
Nzymes started in 1999, a small family company convinced of one simple idea: the body can do far more than we give it credit for, when you hand it the right tools. We are still family-run, still answering the phone ourselves, and still making only a handful of products, each one built to get to the root instead of chasing symptoms.
Over the years we have read thousands of letters from people worried about someone they love and tired of being told nothing more can be done. We started this company for them, and for you. Every consultation with our team is free, because we would rather walk alongside you than sell you a shelf of supplements.
— The Nzymes family
Powered by Nature. Since 1999.
25+
Years, family-run
3
Generations
13
Focused products
FAQs
Common questions.
Understanding Pro-B
Pro-B does two jobs in one daily capsule: live probiotics rebuild the good bacteria your gut runs on, and digestive enzymes break food down so your body absorbs more of it. Most people start it for regularity, comfort after meals, or getting back on track after antibiotics, and stay on it for the steadier everyday digestion.
Most gut supplements pick a side. Probiotics alone re-seed the gut but don't help break food down; enzymes alone break food down but don't rebuild the bacterial balance. Pro-B carries both because the two jobs only make sense together: healthy gut bacteria, and food that's fully broken down so your body can actually use it.
Close cousins. Both pair live probiotics with the same eight digestive enzymes; Bac-Pak Plus comes as a powder you scoop over your pet's bowl, while Pro-B is formulated for people, with higher enzyme strength, in a dissolvable vegetable capsule you take once a day.
Who it's for
Adults should take one capsule daily, per the label. The capsules are hypoallergenic and Non-GMO, with no artificial colors, flavors, or preservatives.
Not as a whole capsule for children. A whole capsule is a choking hazard for anyone who doesn't yet have the ability or skill to swallow one, so we don't recommend capsules for young children. Instead, twist the capsule open and sprinkle the powder into yogurt, applesauce, or a smoothie: same blend, same benefits, no swallowing required.
One note: keep it off hot food or drinks. The probiotics are alive and the enzymes are active, and heat undoes both. Room temperature or cooler keeps them working.
That's one of the most common reasons people start. Antibiotics don't distinguish between bad bacteria and the good populations your gut depends on, so a course often leaves the gut thinned out. Pro-B's probiotics re-seed the good bacteria while the enzymes keep meals landing in the meantime.
Yes: Bac-Pak Plus, the same probiotics-plus-enzymes blend as a powder you scoop over the bowl. Plenty of households run both, one for the people, one for the pets.
Taking it day to day
One capsule a day, on an empty stomach, with 8 ounces of water. First thing in the morning is the easy slot. That's the whole routine, and it's the same for everyone, so there are no tiers to look up.
Starting out? We recommend doubling the daily amount for the first two weeks to give the gut a running start, then settling into one a day.
Each bottle holds 90 capsules: about a 3-month supply for one person, or 6 weeks for a couple sharing.
Most households settle onto a 1–3 month Auto-Ship cadence: 10% off every order, and you're never running out.
Auto-Ship sends your order on a schedule you choose. You save 10% on every order, always, stacked on top of any quantity discount. Pause, change, or cancel anytime from your account.
Then we make it right. Every Nzymes product is backed by our 120 Day Worry-Free Guarantee: if Pro-B isn't a fit, reach out within 120 days for a refund.
And if you're not sure whether it's working, a free consult gets you a real read from our team.
Not sure where to start?
Find your formula.
Answer a few questions and we'll point you to the right starting place — or talk to a member of our team. No guessing, no pressure.