
If you own a gray or white horse, you've probably already run your hand over one of those firm black lumps and felt your stomach drop. Here's what they actually are, why your horse's color matters more than the sun, and what the feed bucket has to do with it.
A melanoma is a cancerous tumor: it forms when the cells that give your horse's skin its pigment start growing where and how they shouldn't, showing up as firm, rounded black lumps on the skin or the soft tissue underneath, usually near areas with little to no hair. Most often they turn up underneath the dock of the tail, in the anal, perianal and genital regions, on the perineum, lips, and eyelids, sometimes near the throat, and often around the head or neck.
Melanomas are the third most common type of skin cancer in horses, behind sarcoids and squamous-cell carcinomas. As a general rule, most are benign, though there have been reports of malignancy. In lighter-colored horses they may grow slowly, sometimes for years, and may never spread to other organs. That's reason to monitor them, not to ignore them.
Roughly 80% of gray horses over the age of 15 have at least one melanoma. Most are superficial and can be monitored for growth, but have the lumps checked by a professional: that's how you get a diagnosis, and depending on severity, some vets prefer taking surgical action early.
In humans, UV rays are thought to be a major factor in melanoma growth. In horses, the research points somewhere else: a mutation of a specific gene, STX17, carried by gray and white horses, is where the melanomas originate. That's why the lumps so often form in places that get little or no sun at all: the crest of the mane, under the tail, inside the mouth.
Nobody has found a way to prevent melanomas yet. What you can control is how early you catch them, and whether the feed bucket is working for your horse or against him.
Sugar content in the diet can contribute to melanomas increasing in growth rate, size, and number. That puts some familiar things on the avoid list for gray horses:
Worth adding to the daily feed: antioxidant mixtures, vitamins C and E, selenium, iodine, zinc, soaked flax seed, and certain mushrooms such as shiitake.
The feeding approach we suggest for melanoma issues comes from Rachel Kitts, a horse owner who developed it over years of trial and error with her own gray horses, including Trinket, the first horse she helped, and Royal, a flea-bitten gray Arabian she adopted from a rescue.
Her starting point was watching how the usual road plays out. When a melanoma is removed by a vet and tested, it usually comes back benign; yet for some reason they always seem to return, and when they return they seem more aggressive, metastasizing sooner. Vets generally rely on leaving the lumps alone, removing them, or injecting drugs into one to see if it goes away. To Rachel, that is treating a symptom and not the problem: there had to be an initial imbalance in the body first to allow bad cells to proliferate. Her research kept pointing at the same thing, a weakened immune system, and since you are what you eat, strengthening it starts with better nutrition.
The sun plays a part, but not the part most people assume. UV radiation is a real stress for animals with naturally weaker immune systems (white and gray horses, albino dogs and cats), and free radicals help cause cancer by changing the genetic material, the RNA and DNA, of the cell. But the lumps so often form where the sun never reaches that radiation can't be the whole story. What sealed Rachel's stress theory was Trinket herself: her worst masses erupted under her tail not long after she gave birth to a foal, and shrank significantly after two months on the Granules.
"Through my own personal studies, I have found a particular feeding regimen combined with Nzymes products that have either halted the formation of new melanomas, made the melanomas dry up and fall off, or shrink in size and fade away."
"Since I have had him, one melanoma on his leg erupted and over a course of a couple weeks dried up and fell off. I feel because I have him on a double dose of the Nzymes Granules and sprayed the area with a 2% solution of the Ox-E Drops daily, both contributed to the body recovering by itself."
Day to day, Rachel keeps it simple: Timothy hay as the main forage with a little Orchard and Oat for variety, the supplements stirred into a wet Timothy-pellet mash ("our horses are in heaven"), free-choice natural salts and minerals, and the Nzymes products below. Alongside the Nzymes line she feeds pure vitamin C (Pure C by VitaFlex), whole flaxseed soaked, never ground or dry, garlic to help keep intestinal parasites down and deter biting flies, and kelp meal (she uses Source) for its packed nutrients. For the salts she buys Redmond, all-natural and right out of the ground; man-made mineral blocks, she's found, don't offer what most horses are lacking.
One more note from her program: alfalfa is a hot feed, and beyond the health risks she's noticed it makes horses take longer to get into a working mindset, "so you are not riding on a 4-legged rocket." The exception is horses in highly physical sports or a mare in foal or lactating; those are the only times she'd add some alfalfa for supplement and variety. Not all cases are the same; some horses improve faster than others, because every body is different. For more on natural horse care, Rachel points readers to Pat Colby's book, which addresses melanomas along with the other illnesses that plague the horse industry.
Trinket, the horse that started it all, has her own page on this shelf: read Trinket's full story →

Whole live super-food that supports the immune system by enhancing the body's own ability to produce its antioxidant enzymes in greater abundance. Enzymes like superoxide dismutase, catalase, and glutathione peroxidase are at the forefront of cellular health: when the cells are better able to perform their functions, better health is the result.
| 600 to 750 lbs | 3 level tsp |
| 750 to 1,000 lbs | 4 level tsp |
| 1,001 to 1,250 lbs | 5 level tsp |
| 1,251 to 1,500 lbs | 6 level tsp |

Digestive enzymes to break nutrients down into usable form, plus probiotics to keep the friendly bacterial flora strong. The GI tract is the centerpiece of your horse's good health and immune function.
| 600 to 1,000 lbs | 2 to 3 scoops |
| 1,001 to 1,250 lbs | 3 to 4 scoops |
| 1,251 to 1,500 lbs | 4 to 5 scoops |

A safe and stable compound of 5% sodium chlorite and reverse-osmosis water, naturally alkaline. Add 20 drops to 10 to 15 cc of filtered water in a large oral syringe, and squirt slowly along the teeth-line so your horse can swallow without choking. It helps maintain a better pH, supports digestion and immune function, and releases precursors that assist the body in cleansing dangerous free radicals and toxins. For melanoma issues you may give it twice daily; the 8 oz Refiller is the practical size.

Spray or apply to the affected areas of the body 3 to 4 times daily for topical support. The Mineral Mist comes pre-mixed and ready to spray. Already have the Ox-E Drops above? You can mix the same spray yourself: 1 teaspoon (80 drops) of the Drops in 8 oz of distilled water in a spray bottle.
All of it is covered by the 120-Day Worry-Free Guarantee: up to four months to see the difference in your own horse.
You can't change a gray horse's genes.
You can change what's in the feed bucket.
Unlike in humans, equine melanomas are not thought to be driven by sunlight. Research points to a mutation of the STX17 gene carried by gray and white horses, which is why the lumps so often form in places that get little or no sun at all.
Very. Roughly 80% of gray horses over the age of 15 have at least one melanoma. Most are benign and grow slowly, sometimes for years, but they should be monitored, not ignored.
Yes. Most melanomas are superficial and can be monitored for growth, but a professional exam is how you get a diagnosis, and depending on severity, some vets prefer taking surgical action early.
Sugar content in the diet can contribute to melanomas increasing in growth rate, size, and number. That means minimizing high-sugar hays like alfalfa, sweet feeds, and treats like carrots, apples, and store-bought cookies. Green vegetables make safer treats.
Four products daily: Sprouted Granules in the feed (doubled the first two weeks), Bac-Pak Plus for digestion and friendly gut bacteria, Ox-E Drops given orally, and the Ox-E Mineral Mist applied to affected areas 3 to 4 times daily.
Kara is the equine specialist on our customer care team, and she keeps her own herd on a farm in Saskatchewan. Tell her what you're seeing, what you're feeding, and what worries you, and she'll tell you honestly where to start. Read Kara's story →
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