A happy dog with its owner
The Wart Support Program

You found the growths. Now find the way through.

Cauliflower-shaped bumps around the mouth, usually in a young, social dog. The vet calls it oral papilloma, and the usual advice is to wait it out while the immune system does its work. This bundle is where we start every family who calls after finding them: support for that immune system, inside and outside, starting today.

4.1 stars from 70 verified bundle reviews · trusted since 1999
The Wart Support Bundle: Antioxidant Treats, Tincture of Black Leaf, Ox-E Drops, and Ox-E Mineral Mist
The Wart Support Bundle
Treats + Black Leaf + Ox-E Drops + Mineral Mist + syringe
$99.99 $112.96 separately
Start the bundle
See if this sounds familiar ↓

Recognize this? You're in the right place.

Side view of a dog's lip and tongue covered in oral papilloma growths
Side view · lip and tongue growths
An Australian Shepherd with visible mouth growths, 5 days in
Mouth growths · after 5 days
Chin view of the same dog's growths at 9 days
Chin view · after 9 days
Front view of the same dog at 11 days
Front view · after 11 days
01Does this sound familiar?

You spotted one bump.
Then you counted more.

It usually starts during a yawn or a game of tug: a pale, rough little growth on the lip or gums you're sure wasn't there last week. The vet visit brings a name — canine oral papilloma, a virus young dogs pass around the way kids pass colds — and advice that's hard to sit with: wait, and let the immune system handle it. So you watch the growths multiply while you're told to do nothing. That's how most families find this page.

The counting

You check the mouth every day now. Two became five, five became a cluster, and every new one makes waiting feel more wrong.

The benched season

Daycare, the dog park, the playdates that made your dog who she is — on hold, because it spreads dog to dog. A social dog, suddenly grounded.

The helpless feeling

You'd do anything for this dog, and the plan on the table is to do nothing. Every day of waiting feels like a day of not helping.

"Wait it out" isn't a plan. Supporting the immune system is.

02Here's what's really going on

The answer isn't surgery.
It's the immune system.
So let's give it what it needs.

Oral papilloma clears when a dog's own immune system takes over — and the vet is right that it usually gets there on its own. The part we'd never accept is doing nothing while you wait. This bundle backs the immune system from every direction: live whole-food nutrition underneath, botanical and pH support inside, and a mineral mist for the outside. Your dog's body does the work. You make sure it's equipped.

The foundation · from your hand daily
Antioxidant Treats, the shield

Live, sprouted whole-food nutrition plus vitamins A, C, and E with selenium — the raw materials an immune system draws on when it has real work to do. Doubled for the first two weeks while the body restocks.

Black Leaf
The inside team · drops, twice daily
Black Leaf + Ox-E Drops, the inside team

Tincture of Black Leaf is the herbal defense: black walnut, olive leaf, and cayenne, backing the fight already underway. Ox-E Drops balances the immune system's response from within. Both by syringe, or straight into food or water.

Ox-E Mineral Mist spray bottle The outside touch
The outside touch · spray as directed
Ox-E Mineral Mist, right where it counts

The same Ox-E support in a gentle topical mist — sprayed directly where the growths are. Inside and outside, the whole job is covered.

Not "wait and see." Wait and support.

Convinced already? Start the bundle →

03Proof from real families

We've been taking this call for decades.

Biscut, the founders' Japanese Spitz, in a family snapshot from 1999
Biscut, 1999. The dog who started it all.
Where Nzymes began

We were built for the calls nobody else takes.

Nzymes exists because in 1999, a dog named Biscut was in trouble and her family — ours — refused to accept "there's nothing to do." Our co-founder Stan and his brother Tom went looking at nutrition when almost nobody was, and the formulas they built have been supporting dogs' own defenses ever since. The wart call, a worried family with a young dog and a "wait it out," is one we've answered for decades.

Read Biscut's full story →
Seen on real dogs

The before-and-afters families send us.

Use the Back and Next buttons to see all nine dogs. Tap Read the full story under any dog to hear what their family did.

4.1★
Average from real families
80%
Rated 4–5 stars
120days
Worry-free guarantee
★★★★★

“At 7 months our pup got oral papillomas from day care and we were advised from our vet that they would go away in 4-6 weeks. 6 weeks went by and they hadn't gone away… they actually looked like they were getting bigger and she was getting more of them. We decided to try this product and they started to get smaller after the first week. By the 3rd week they were gone. Sure wish we would have tried this at the beginning!! If you are debating to give it a try, do it!”

Smaller in week 1 · gone by week 3

Aly · Verified review

★★★★★

“My vet told me that it would take 3-6 months for my dog to get over the Papilloma virus in his mouth. I used the Papilloma support kit and he was over the virus in 3 weeks. Worked great.”

3 weeks

Marjorie N. · Verified review

★★★★★

“At the beginning I was very upset because the papilloma did not improve as soon as I expected… I was contacted by customer service and they explained how the treatment worked fast in some pets and not that fast in another. I continued using and until about 4 weeks we started seem the warts shrinking until they all disappeared.”

Turning by week 4

Nyria G. · Verified review

★★★★★

“After about 2.5 weeks this really started to work. You really need to follow the instructions but it WILL work! Thank you!”

2½ weeks

Shelly · Verified review

Individual experiences shared by real customers, not promises and not a substitute for veterinary care. The Wart Support Bundle is nutrition and topical care, not a treatment for oral papilloma, warts, or any disease; every dog is different and individual results may vary.

★Straight from Judge.me

More families, in their own words.

A live, revolving feed of verified Wart Support Bundle reviews, updated automatically as new ones come in.

You don't have to do it alone

Talk it through with a member of our team.
It's free.

We're a small family team, and we've talked hundreds of families through exactly this. Tell us what's going on with your dog's mouth, what the vet said, how long it's been, and we'll help you get the routine right and set honest expectations. We walk alongside you, from the first day on.

04The way through is simple

Three steps. Three minutes a day.

1
Pick your dog's size

Under 25 lbs, the Small Dogs bundle with Tiny Treats. 25 lbs and up, the Standard. That's the only decision you have to make.

2
Inside, then outside

A treat from your hand, drops by syringe or in the bowl, and a quick spray of the mist where the growths are. Anchor it to breakfast and it's done in about three minutes.

3
Photograph weekly

Double the treats the first 2 weeks while the body restocks, then settle in. Take one photo of the mouth each week; it's the honest way to see what's changing.

Included with every bundle

And none of it is on you to memorize. Your interactive step-by-step guide, with your dog's exact amounts, how to give each product, and what to expect week by week, arrives by email the same day you order. Our team checks in a few weeks later. Questions before then? The consult is always free.

05The decision families face

The easy decision,
before the expensive ones.

Every road in front of you is real. Here's what each one costs.

The road you may be on

Expensive, slow, and a lot of trial and error.

Surgical removal under anesthesia — a real bill and a real procedure, and it doesn't address the virus, so new growths can still follow.
"Wait it out" — months of daily mouth checks and a benched, grounded dog, while the growths spread before they retreat.
Hours of late-night research into home remedies of every kind, with no one to tell you which are safe and which are wishful thinking.
The step you can take today

Simple, affordable, and it starts this week.

Three minutes a day, at home: a treat, a few drops, a quick spray. No anesthesia, no waiting rooms, no doing nothing.
About a dollar a day for the whole inside-and-outside routine, a fraction of a single surgical estimate.
120 days to see the difference, and a full refund of the unused portion if you don't. Trying is never the risk.
$99.99the complete bundle · $96.99 for small dogs
Make the easy decision first →
Surgical removal, under anesthesia
$600–$1,400

What families in our reviews report paying. And surgery removes growths, not the virus behind them, so new ones can still follow. One reviewer's warts “were growing back within 3 days.”

“Wait and see”
3–6 months

The usual estimate while the immune system finds its answer alone. Months of daily mouth checks, cancelled daycare, and a benched, grounded dog.

The Wart Support Bundle
$99.99

About a dollar a day for the whole inside-and-outside routine, at home, starting this week. Covered by the 120 Day Worry-Free Guarantee, so trying is never the gamble.

Make the easy decision first →

Surgery figures come from this bundle's own verified reviews; your vet's estimate may differ.

06The destination

Three months from now.

The weekly photos are still on your phone, and you've stopped dreading taking them. The routine has become just that: a treat, a few drops, a quick spray, done before breakfast. The mouth checks feel less like a vigil and more like a habit, and the playdates are back on the calendar. It's not a treatment, and we would never call it one. It's just steady support for the immune system doing its own job.

Choose your bundle ↓
What's in the box

Inside and outside,
the whole job covered.

A bottle of Nzymes Antioxidant Treats
×1 bottle · 60 treats
Antioxidant Treats

The foundation, from your hand once a day. To your dog, it's just a treat. Small-dog bundles include Tiny Treats instead, sized for smaller mouths.

A bottle of Nzymes Tincture of Black Leaf
×1 bottle · 2 oz tincture
Tincture of Black Leaf

Botanical drops, twice a day, by syringe or stirred into food. Black walnut, olive leaf, and cayenne in one time-honored blend.

A bottle of Nzymes Ox-E Drops
×1 bottle · 2 oz drops
Ox-E Drops

A few drops, twice a day, supporting healthy pH and oxygen balance from the inside while the treats and botanicals do their work.

A bottle of Nzymes Ox-E Mineral Mist
×1 bottle · 4 oz spray
Ox-E Mineral Mist

The outside touch: a gentle mist applied right where the growths are.

Included free A 5 ml oral dosing syringe
×1 · oral syringe
Oral syringe

For exact, easy drops straight by mouth, no guessing, no wrestling with a dropper over the food bowl.

Included free The Nzymes paw print
In your inbox · the same day you order
Interactive step-by-step guide

Your dog's amounts, how to give each product, and what to expect week by week. Emailed to you the same day you order.

Every formula: human-grade ingredients · non-GMO · made in the U.S.A. since 1999.

Your only decision

The complete bundle,
under $100.

All four formulas and the syringe, paired and sized for your dog, automatically discounted 10% versus buying the pieces separately. One box, one price, one decision, and the way through begins. No commitment required: most dogs need exactly one bundle, so that's all we ask you to buy.

Most popular The Wart Support Bundle, standard size
Recommended for your dog
Wart Support Bundle
Dogs 25 lbs & up
$99.99$112.96 separately
You save $12.97

One-time purchase, no commitment: the bundle is automatically discounted 10% versus buying the pieces separately.

Add to cart

Antioxidant Treats + Black Leaf + Ox-E Drops + Mineral Mist + oral syringe

For dogs under 25 lbs The Wart Support Bundle for small dogs, with Tiny Treats
Recommended for your dog
Wart Support Bundle for Small Dogs
Dogs under 25 lbs · with Tiny Treats
$96.99$109.96 separately
You save $12.97

One-time purchase, no commitment: the bundle is automatically discounted 10% versus buying the pieces separately.

Add to cart

Tiny Treats + Black Leaf + Ox-E Drops + Mineral Mist + oral syringe

Covered by our 120 Day Worry-Free Guarantee. Four full months to see the difference, or your money back.

“The vet did surgery, cost me $600, to remove the warts on my dogs mouth area. They were growing back within 3 days. I found Nzymes on line with tons of info. I bought the kit and within 3 weeks my dogs was wart free.” Rachel · Verified review

FAQs

Common questions.

Understanding the bundle

One bottle of Antioxidant Treats (or Tiny Treats, for dogs under 25 lbs), Tincture of Black Leaf, Ox-E Drops, Ox-E Mineral Mist, and a free oral syringe. The same day you order, your interactive step-by-step guide arrives by email, spelling out the whole routine. It's the program we recommend to families who call about oral papilloma: the treats bring live, sprouted nutrition and antioxidant support underneath, the Black Leaf and Ox-E Drops support from the inside, and the mist works right where the growths are.

Canine oral papillomavirus is a virus that causes rough, cauliflower-shaped growths in and around the mouth, most often in young dogs whose immune systems haven't met it yet. It passes dog to dog through play, shared toys, and water bowls, which is why it shows up after daycare and dog parks. In most dogs the immune system eventually clears the virus and the growths go away on their own, which is why many vets advise waiting it out. Some vets also recommend surgery, which is expensive and not guaranteed to stop the warts from coming back. This bundle exists for families who want to support their dog's immune system instead of only waiting, and who'd rather not risk a costly procedure that may not hold.

Because the job has an inside and an outside. The treats are the foundation: whole-food nutrition and antioxidant support for the body doing the work. Black Leaf adds traditional botanical defense, Ox-E Drops supports healthy pH and oxygen balance internally, and the Mineral Mist brings the same support directly to the growths themselves. Each piece has one job; together the whole job is covered.

Warts, timelines & your vet

That's the question you came here with, and we'll answer it as honestly as the law rightly requires: the Wart Support Bundle is nutrition and topical care, not a drug, so it doesn't treat, cure, or remove warts, papillomas, or any disease. Clearing the virus is your dog's immune system's job — even your vet will tell you that part. What this bundle does is make sure that immune system has the raw materials, the botanical support, and the direct topical care while it works.

What we can tell you: families have been calling us about exactly this for decades, and the routine you're looking at is where we start every one of them. And here's how confident we are: take four full months, and if you don't see the difference, the 120 Day Worry-Free Guarantee returns your money. We carry the risk, so trying is never the gamble.

Both of those roads are real, and your vet knows your dog. Surgery removes growths but not the virus behind them; waiting relies entirely on the immune response this bundle is built to support. Many families run the bundle while they wait, precisely so the waiting isn't doing nothing — and it works alongside whatever your vet recommends. If you're weighing a surgical estimate right now, book a free consultation first. The conversation is free, and it may be the most useful fifteen minutes of the whole decision.

Every dog meets this virus on its own timeline, so we won't pretend to know yours. Coat, skin, and energy changes from the treats often show up within the first few weeks; the mouth itself is why we recommend the weekly photo, because gradual change is hard to see day to day and obvious week to week. The keys are consistency and following the protocol as written, including the doubled treat start. And the 120-day guarantee means you have four full months to watch it happen.

Oral papilloma does pass from dog to dog, which is why it moves through daycares and dog parks, and most facilities will ask an affected dog to sit out while growths are visible. How long to bench your dog, and how careful to be with shared bowls and toys at home, deserves a real conversation about your situation: book the free consult and we'll talk it through, along with what other families in your shoes have done.

Day to day

The treat comes from your hand once a day (doubled for the first two weeks). The Black Leaf and Ox-E Drops go in twice a day, by the included syringe or stirred into food or water. The Mineral Mist sprays directly onto the growth areas as directed on the label. Anchor it all to breakfast and dinner and the whole routine takes about three minutes a day. The step-by-step guide emailed with your purchase spells out the exact amounts for your dog's weight.

The treats are savory and most dogs take them straight from your hand on day one; if yours doesn't, they crumble over food (1 level teaspoon of crumble equals 1 treat). The drops bypass pickiness entirely with the syringe, and the mist never touches the food bowl at all. And if it truly doesn't work, the guarantee covers picky eaters too.

Oral papilloma is mostly a young dog's condition, so this question comes up a lot. The daily amounts scale by weight, and the Small Dogs bundle covers dogs under 25 lbs. For very young puppies or a complicated case, give us a call before you start and we'll help you set the routine.

Ordering & our guarantee

Usually not. Oral papilloma is a fight that ends, and for most dogs one bundle covers it. That's why the bundle is a simple one-time purchase at a built-in discount, with no commitment attached. Our team checks in a few weeks after your order arrives to see how things are going; if your dog turns out to need a longer runway, we'll help you figure out exactly what to reorder and nothing more.

The Wart Support Bundle is covered by our 120 Day Worry-Free Guarantee. Try it with your dog for up to four months. If you don't see a difference, return the unused portion for a full refund. No questions asked.

You don't need to just wait it out. You need a way through.

Your dog's immune system is already on the job. This bundle makes sure it's equipped. If you're not sure it's right for your dog, ask us first; the conversation is always free.

Or talk it through first, free: 1-877-816-6500 (toll-free) · 1-702-228-0097 · customer.care@nzymes.com