Guide · 4 min read

Asthma in Dogs:
The Triggers, Missing Enzymes, and What You Can Do

First published April 2014 · Revised 2026From the Respiratory & Kennel Cough shelf

If you've watched your dog fight for a breath, you already know how frightening an asthma episode is. Something sets it off, the airways tighten, inflammation and mucus follow, and it gets harder still. Research has tied asthma to low levels of certain antioxidant enzymes, and that's where daily nutrition can do some real good. Here's what to know, and what you can do.

What happens in an episode

Asthma is a condition that comes and goes. Between episodes your dog seems perfectly fine. Then something sets one off: the airways tighten and breathing gets hard. Inflammation follows, along with extra mucus in the lining of the airway. That narrows things further, and it gets harder still.

The triggers. Families tell us all kinds of things set one off. Excitement or stress, a hard run, overdoing it at the park. So can what's in the air: allergens, chemicals or household cleaners, even a swing in temperature or humidity. (Our guide to dog respiratory problems has more on the irritants that live inside the house.)

Antioxidant enzymes and asthma

Here's the part most people haven't heard. Researchers have found a link between certain antioxidant enzymes and asthma. When three of them, superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx), are running low, asthma is more common (see the NIH article), and in dogs and people who already have it, the lower the SOD, the harsher the episodes.

Why more of these enzymes is a plus. Superoxide dismutase is a front-line antioxidant enzyme. Its job is to catch a damaging free radical and turn it into something harmless before it can hurt cells and stir up inflammation. In some models of lung inflammation, enzymes like SOD rise to meet the stress and limit the damage. In an asthmatic airway, that defense doesn't rise the way it should.

The open question. What nobody knows yet is which comes first: whether an episode temporarily shuts down the antioxidant defense, or whether running low day to day is what leaves the door open for episodes. Either way, it makes sense to give the body what it needs to keep up its own production of SOD and the other antioxidant enzymes.

Where Nzymes can help

Nzymes Breathe Easy BundleThe Breathe Easy BundleAntioxidant Treats and Ox-E Drops together, with the interactive step-by-step guide for the bowl and the vaporizerSee the program →

That's why the Breathe Easy Bundle is where we start for an asthmatic dog. Antioxidant Treats handle the inside job: the live sprouted enzymes and added antioxidants give the body the raw materials it needs to keep making SOD and the other antioxidant enzymes. It's the daily foundation, and asthma is exactly the kind of thing it's built for.

Secondary bacterial trouble. Asthmatic airways pick up secondary bacterial trouble more often than you'd think, which is why the bundle's second half matters just as much. Ox-E Drops are the product families have reached for over twenty-five years to support clear airways, in the water bowl and in a vaporizer. The bundle puts both products together, with the interactive guide that walks you through each step, including the vaporizer.

Not sure whether it's asthma or something else? Tell us what you're hearing and when it happens. We'll listen. Book a free consultation →

An inhaler quiets the episode.
The antioxidant defense underneath
is what's been running low.

Seven families watched their dog breathe easy again
CaesarPennyAbbyEmmet
Caesar, Penny, Abby, Emmet and three more, in their families' own words →
Questions families ask
How do I know it's asthma and not kennel cough?

Asthma comes in episodes, often with a trigger you can name (stress, exertion, a cleaning product, a weather change), and the dog is fine between them. Kennel cough is a steady, hacking cough that arrived after exposure to other dogs and runs its course. If you're not sure which you're hearing, book a free consultation and describe it. We'll tell you honestly what it sounds like, including whether a vet visit makes sense.

Is an asthma episode an emergency?

It can be. If your dog is struggling to breathe, breathing with an open mouth at rest, or has blue or grey gums, that's a vet visit right now. The nutritional support here is for the long game between episodes, not for the middle of one.

Why does the bundle pair Antioxidant Treats with Ox-E Drops?

Because asthma has two sides. The research points at low antioxidant-enzyme activity, and the Treats are the product built to supply the raw materials for the body's own production of SOD. That's the daily foundation. Ox-E Drops cover the other side: asthmatic airways commonly pick up a secondary bacterial problem, and the drops support clear airways in the water bowl and the vaporizer. The Breathe Easy Bundle puts both together, with the interactive guide that walks you through each step.

What does Nzymes recommend?

The Breathe Easy Bundle, for any respiratory condition including asthma. Antioxidant Treats daily for the enzyme support underneath, and Ox-E Drops in the water bowl and the vaporizer for the airways themselves. The bundle includes an interactive guide, sent to your inbox after purchase, with exact amounts and steps for your dog's size. If you'd like to talk it through first, our free consultation is always there.

Next guide · 3 of 7Bronchitis in Dogs: What to Know →
Questions along the way

Reading explains it. The Breathe Easy Program walks you through it.

Asthma is one where families most often want help telling an episode apart from an infection, and deciding whether the Treats alone are enough. Book a free consultation and tell us what you're hearing, when it happens, and what your dog is taking, and we'll tell you honestly what it sounds like, including whether a vet visit makes sense.

The consultation is a scheduled half hour with the people who have walked hundreds of families through this, so you get real time and real answers instead of a rushed phone call. It's free, and it always will be.

Mike Stan Brenda Kara
1-877-816-6500 · Orders & quick questions
The Breathe Easy Bundle
The Breathe Easy Bundle